Membrane Fluidity Measurements Using UV Fluorescence Polarization and the POLARstar Omega 21 Apr 2010: In this application note the POLARstar Omega microplate reader from BMG LABTECH was used to study membrane fluidity via fluorescence polarization in the UV range. The method allows for the monitoring of large scale alterations in membrane fluidity (such as phase transitions), as well as more subtle changes in lipid dynamics. BMG LABTECH
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Porvair Announces Latest Version of the MiniVap-96 for Rapid Microplate Solvent Removal
15 Apr 2010: Incorporating advanced evaporator head technology and an innovative manifold design, which directly injects heated nitrogen into each well of a 96-well microplate simultaneously, the affordable MiniVap™ from Porvair Sciences takes just minutes to remove volatile organic solvents from your plate. Porvair Sciences Ltd
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BMG LABTECH Announces First FP User Group Meeting
14 Apr 2010: BMG LABTECH world leader in microplate reading technology and developers of the first fluorescence polarisation microplate reader, POLARstar, are pleased to announce their inaugural UK Fluorescence Polarisation (FP) user group meeting on the 23rd of April 2010. BMG LABTECH
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Syrris Launches New Atlas Hot and Cold Plate for Regular Hotplate Stirrers
12 Apr 2010: Fitting on virtually any magnetic stirrer or stirrer hotplate, the Hot and Cold Plate provides operating temperatures from -40°C to +160°C. Its ultra low profile maintains a strong coupling between the stirrer and stirrer bar, ensuring the highest quality stirring. Syrris Limited
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Visit R&D Systems at AACR to View the New Microplate-based Antibody Array
12 Apr 2010: R&D Systems presents the Proteome Profiler™ 96 Microplate-based Antibody Array. Register at R&D Systems' booth (#2152) for a chance to win a copy of Rebecca Skloot's The Immortal Life of Henrietta Lacks - the true tale of the woman behind HeLa cells. R&D Systems, Inc.
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Automation of Multiplexed Cell-Based Assay to Measure Induction of Gene Expression and Activity of Cytochrome P450 Isoform 3A4 08 Apr 2010: This application note demonstrates the automation of a cell-based multiplexed assay to explore how a drug can induce gene expression and inhibit activity of the same isoform, creating a useful tool to measure the stimulatory and inhibitory effects of a drug. Activity and induction of gene expression of CYP3A4 were measured using a luminogenic, cell-membrane permeable 3A4-specific substrate and a luciferin based reporter gene assay. BioTek Instruments, Inc.
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Nephelometric Monitoring Growth of Candida albicans Using BMG LABTECH’s NEPHELOstar 08 Apr 2010: Laser nephelometry has been shown to be a reliable technique for the measurement of drug solubility in 96-well plate format. In this application note the effects of complexation on drug antimycotic activity is described. Laser nephelometry can distinguish between the concentration at which the drug just goes into or just comes out of solution. This is presented in phase solubility studies. BMG LABTECH
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Pathway-Focused Gene Expression Panels Validated for Real-time PCR
07 Apr 2010: Fluidigm Corporation and SABiosciences (a QIAGEN Company) have announced that they have teamed up to create over 100 pathway-focused gene expression panels validated for real-time PCR analysis on the Fluidigm BioMark™ System for Genetic Analysis. These kits are named the RT² Profiler™ PCR Arrays for the Fluidigm BioMark system. Fluidigm Corporation
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AACC Announces 2010 Annual Meeting Plenary Session 06 Apr 2010: The American Association for Clinical Chemistry (AACC) is holding its 2010 Annual Meeting & Clinical Lab Expo July 25 - 29 at the Anaheim Convention Center, Anaheim, CA. The highlight of each day is the Plenary Session which provides a unique opportunity to hear from world leaders in the areas of science, medicine and technology. AACC
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CYTOO Cell Architects will be Introducing CYTOOplates™ at SBS 2010
06 Apr 2010: CYTOOplates™ feature thousands of adhesive micropatterns on an optical glass surface that reduce variability, simplify quantitative analysis, and improve reproducibility in HCA/HCS and other cell-based assays. The poster entitled "Adhesive micropattern use in High Content Screening: a case study" will also be presented. CYTOO Inc.
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