Microplate-Based Endotoxin Testing in GLP/GMP Environments with the VersaMax™ Absorbance Microplate Reader and Pyrochrome® Assay 07 Jun 2010: This application note describes a typical set-up for a standard curve in the Pyrochrome® Assay. The Pyrochrome® Assay together with the VersaMax Microplate Reader offers a sensitive and specific method for detecting endotoxin contamination in the production process of the pharmaceutical and medical device industries. Molecular Devices
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Stem Cell-Derived Human Neurons in CNS Drug Discovery 07 Jun 2010: In this application note from Molecular Devices reproducible batches of human neurons are generated that will significantly improve and impact CNS drug discovery. The stem cell-derived neurons express all known markers typically associated with mature neurons and are functionally active. These neurons have been used in a recent screen to identify antagonists of a novel GPCR target implicated in schizophrenia. Molecular Devices
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Cytotoxicity in Cells: Easy Determination Using Lonza ViaLight Plus and ToxiLight BioAssays on the SpectraMax L Microplate Luminometer 07 Jun 2010: The Lonza ViaLight® Plus and ToxiLight® Bioluminescent Cytotoxicity Assays exploit the cell characteristics of ATP levels and adenylate kinase release respectively, as cytotoxicity measures and enable detection using bioluminescent methods. This application note demonstrates that the SpectraMax L Microplate Luminometer and SoftMax Pro Software from Molecular Devices combine well with both assays providing a fast and sensitive combination of technologies in the field of cell death. Molecular Devices
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Acumen eX3 Speeds up Invasion and Migration Studies 04 Jun 2010: TTP LabTech has joined forces with Platypus Technologies to offer automated solutions for studying the migration and invasion profiles of different cell lines using the Acumen eX3 laser scanning microplate cytometer. TTP LabTech
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TTP Labtech Announces New Validated Cell Colony Formation Assay for Acumen eX3
04 Jun 2010: TTP LabTech has validated a new cell colony formation assay on the Acumen® eX3 fluorescence microplate cytometer in collaboration with ChemPartner. As an alternative to the traditional method this latest protocol uses fixed as opposed to live cell colonies for analysis. TTP LabTech
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BellBrook Labs Launches New Microplate for High Content Chemotaxis Assays in a Stable Gradient
03 Jun 2010: BellBrook Labs announces that it has completed successful field testing on their iuvo Chemotaxis Assay Plate and is transitioning the product to a full commercial launch. The plates provide drug discovery researchers with high quality data on the potency of compounds that affect neutrophil chemotaxis, a key goal for intervening in inflammatory diseases and disorders. BellBrook Labs
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AchemAsia Draws Process Engineers, Chemists and Many More to Beijing 01 Jun 2010: With 413 registered exhibitors, AchemAsia opens on June 1st, 2010, at the China National Convention Center in Beijing. Organizers DECHEMA and CIESC together with their partners expect more than 15,000 visitors at the 8th International Exhibition-Congress on Chemical Engineering and Biotechnology. Dechema
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Porvair Sciences Announces New Range of Aluminium Heat Seals for PCR, Storage & Life Sciences Applications
25 May 2010: The new foils are precision engineered to an exact thickness and come colour-coded to enable easy identification of the different types. In addition, the pre-cut foil sheets are marked to ensure that they are always used the right way up, thus minimising possible damage to the sealing head of a thermal heat sealer. Porvair Sciences Ltd
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Using EL406™ Combination Washer Dispenser to Semi-Automate an ELISA for Melamine 24 May 2010: Melamine is a nitrogen rich compound that has been used illegally as an additive that mimics protein in foods. This application note demonstrates the ability of the EL406 to automate the liquid handling tasks required to run the melamine ELISA kit from Abraxis. The melamine ELISA has the capability to detect melamine contamination in the parts per billion (PPB) ranges. BioTek Instruments, Inc.
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Turbidometric Growth Curve Measurements and Liquid Evaporation Studies with a Microplate Photometer 24 May 2010: The ability to monitor bacterial samples is important for food testing safety and analysis. This paper describes how a filter-based microplate photometer, Thermo Scientific Multiskan FC, can be used reliably and easily to measure turbidity of bacterial samples in antibiotic susceptibility studies. The growth curve measurements were performed on a 96-well microplate. Thermo Fisher Scientific
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